EQUILIBRIUM SEDIMENTATION OF MACROMOLECULES IN DENSITY GRADIENTS
- 15 July 1957
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 43 (7) , 581-588
- https://doi.org/10.1073/pnas.43.7.581
Abstract
A new method for the study of the molecular weight and partial specific volume of macromolecules, with some illustrations based on results with deoxyribonucleic acid (DNA) and several viruses. The method involves observation of the equilibrium distribution of macromolecular material in a density gradient itself at equilibrium. The density gradient is established by the sedimentation of a low-molecular-weight solute in a solution subject to a constant centrifugal field.This publication has 3 references indexed in Scilit:
- Studies in Mutagenesis: Production of Bacteriophage Mutants by a Disturbance of Deoxyribonucleic Acid MetabolismNature, 1956
- THE GLUCOSE CONTENT OF THE DEOXYRIBONUCLEIC ACIDS OF CERTAIN BACTERIOPHAGESProceedings of the National Academy of Sciences, 1956
- A New Pyrimidine Base from Bacteriophage Nucleic AcidsNature, 1952