Safety and Efficacy of Antimicrobial Peptides against Naturally Acquired Leishmaniasis
- 1 February 2004
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (2) , 641-643
- https://doi.org/10.1128/aac.48.2.641-643.2004
Abstract
Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.Keywords
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