Enantioselective Synthesis of Optically Pure Amino Alcohol Derivatives by Yeast Reduction
- 5 January 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 16 (1) , 129-132
- https://doi.org/10.1246/cl.1987.129
Abstract
Baker’s yeast reduction of nitro- and imide-containing ketones gives the corresponding secondary alcohols in good yields with excellent optical purity. Among the imide groups examined, the ketones with saccharin moiety give the products in the best chemical and optical yields.Keywords
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