Effect of Fasting and High-Fat Diet Feeding on Plasma and Pancreatic Insulin Contents in Young Chick Given an Oral Glucose Load
- 1 January 1972
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 4 (05) , 337-341
- https://doi.org/10.1055/s-0028-1094028
Abstract
Experiments were conducted to determine the effect of fasting or high-fat diet feeding on the pancreatic insulin content and on the plasma insulin response of the chicks to an oral glucose load. Thirty-hour-old chicks not fed and one-week-old high-fat diet fed chicks showed a significant response. One-week-old mash-fed 30 hr fasted chicks showed a greater rise in insulin level in response to glycemic stimulus. On the other hand one-week-old mash-fed chicks showed the poorest response. The pancreatic insulin content (units/100 gm body weight) of the 30 hr old chicks was significantly lower than those of other three groups. The results suggest that chick when fasted or fed a highfat diet, in contrast to rat, maintains its responsiveness to a glycemic stimulus. 1 This work was supported in part by NIH grants AM 05410-10 and 5T 01 GM 00293Keywords
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