Serum levels of soluble CD30 in adult patients affected by atopic dermatitis and its relation to age, duration of disease and Scoring Atopic Dermatitis index
Open Access
- 1 January 2000
- journal article
- research article
- Published by Wiley in Mediators of Inflammation
- Vol. 12 (2) , 123-125
- https://doi.org/10.1080/0962935031000097736
Abstract
The value of CD30 and the soluble circulating fragment of CD30 (sCD30) for atopic dermatitis (AD) remains unclear. In particular, little is known about the effects of age, duration of disease and Scoring Atopic Dermatitis index (SCORAD) on the levels of serum sCD30 in patients affected by AD. In the present study, we have analysed serum sCD30 levels of adult patients affected by AD. The study's population includes 18 non-smoking outpatients, with a diagnosis of AD. As a control group we studied 18 non-atopic subjects from laboratory staff, matched for sex and age. These subjects had no history of AD, urticaria or seasonal or perennial rhinitis or asthma, and had negative skin prick test to a panel of allergens.Keywords
Funding Information
- Ministry of Education, Universities and Research
This publication has 12 references indexed in Scilit:
- New insights into the role of T cells in atopic dermatitis and allergic contact dermatitisTrends in Immunology, 2001
- [Pathogenesis and guidelines for therapy of atopic dermatitis].2001
- Role of CD30+ T cells in rheumatoid arthritis: a counter-regulatory paradigm for Th1-driven diseasesTrends in Immunology, 2001
- Soluble CD30 and Cyclosporine in Severe Atopic DermatitisInternational Archives of Allergy and Immunology, 2000
- Pathogenesis of atopic dermatitisJournal of Allergy and Clinical Immunology, 1999
- IFN-γ is only partially restored by co-stimulation with IL-12, IL-2, IL-15, IL-18 or engagement of CD28Clinical and Experimental Allergy, 1999
- In vivo CD30 expression in human diseases with predominant activation of Th2-like T cellsJournal of Leukocyte Biology, 1997
- Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis.Journal of Clinical Investigation, 1994
- Lesional expression of interferon-γ in atopic eczemaThe Lancet, 1994
- Differential Cytokine Profiles in Peripheral Blood Lymphocyte Supernatants and Skin Biopsies from Patients with Different Forms of Atopic Dermatitis, Psoriasis and Normal IndividualsInternational Archives of Allergy and Immunology, 1994