LACTATE CONCENTRATIONS IN PRE-OVULATORY FOLLICLES OF PRO-OESTROUS RATS BEFORE AND AFTER ONSET OF OOCYTE MATURATION

Abstract
Lactate concentrations were determined in pre-ovulatory follicles of rats at proestrus before and after onset of oocyte maturation. It appeared that high concentrations prevail before and after the time of the expected LH [luteinizing hormone] surge (27 mM). The level in serum was about 5 mM. Explanted oocytes obtained from prepuberal rats and surrounded by cumulus cells, matured in the presence of 20 mM lactate as the sole exogenous energy source. O2 may be the limiting factor suppressing oocyte maturation in vivo.

This publication has 2 references indexed in Scilit: