Key Variables in Dosage form Design
- 1 January 1991
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 17 (7) , 959-974
- https://doi.org/10.3109/03639049109040832
Abstract
The study described herein was undertaken to learn more about the relationships between tablet properties and formulation/process variables. Five independent variables were varied according to a central composite star design, and a number of properties have been evaluated. A discussion of various statistical procedures/issues have been examined for exploratory studies such as this one.Keywords
This publication has 8 references indexed in Scilit:
- Formula Optimization for a multiple Potency System with Uniform Tablet WeightDrug Development and Industrial Pharmacy, 1986
- Reversed-phase high-performance liquid chromatography of sulindac and related compounds using a computer simulationJournal of Chromatography A, 1983
- Optimization techniques: Studies in cell cultureDrug Development and Industrial Pharmacy, 1983
- Optimisation in pharmaceutical sciencesInternational Journal of Clinical Pharmacy, 1981
- Selecting Key Pharmaceutical Formulation Factors by Regression AnalysisDrug Development and Industrial Pharmacy, 1979
- Selecting Key Parameters in Pharmaceutical Formulations by Principal Component AnalysisJournal of Pharmaceutical Sciences, 1975
- Computer Optimization of Pharmaceutical Formulations II: Application in TroubleshootingJournal of Pharmaceutical Sciences, 1973
- Computer Optimization of Pharmaceutical Formulations I: General procedureJournal of Pharmaceutical Sciences, 1973