Radical Scavenging Activities of Niacin-Related Compounds
- 1 January 2002
- journal article
- Published by Oxford University Press (OUP) in Bioscience, Biotechnology, and Biochemistry
- Vol. 66 (3) , 641-645
- https://doi.org/10.1271/bbb.66.641
Abstract
We investigated whether niacin-related compounds had radical-scavenging activity by electron spin resonance methods. Many compounds, but not trigonelline, had radical-scavenging activity against hydroxyl radicals. However, for the nitric oxide radical and 1,1-diphenyl-2-picrylhydrazyl radical, only nicotinic acid hydrazide and isonicotinic acid hydrazide had scavenging activities. These results suggest that the moiety of hydrazide might have an important role in scavenging abilities of various radicals.Keywords
This publication has 3 references indexed in Scilit:
- ADP-Ribosylation ReactionsPublished by Springer Nature ,1992
- [9] Spin-trapping methods for detecting superoxide and hydroxyl free radicals in vitro and in vivoPublished by Elsevier ,1990
- ADP-Ribose Transfer ReactionsPublished by Springer Nature ,1989