The Impact of Lithium in South-West Scotland III. The Discontinuation of Lithium

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Abstract
Summary: A review in South-West Scotland of all patients prescribed lithium for the first time during the years 1972–82 showed that on average, 12 per 100,000 of the general population start this drug each year. By the end of the period, lithium had been stopped in 58% of patients; the most common reason for discontinuation was the development of side-effects, of which tremor was the most frequent. In only 15% was lithium stopped as it was considered no longer necessary; 44% of patients discontinued lithium within one year of starting it.