Daucane Sesquiterpenes from Ferula hermonis
- 1 March 2001
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 64 (3) , 399-400
- https://doi.org/10.1021/np000526x
Abstract
The roots of Ferula hermonis Boiss yielded two new daucane esters, 14-(4‘-hydroxybenzoyloxy)dauc-4,8-diene (1) and 14-(4‘-hydroxy-3‘-methoxybenzoyloxy)dauc-4,8-diene (2), together with the four known sesquiterpenes jaeschkeanadiol p-hydroxybenzoate (3), jaeschkeanadiol benzoate (4), jaeschkeanadiol (5), and epoxyjaeschkeanadiol (6). The identities of the isolated compounds were ascertained primarily using NMR and MS data. Compounds 1 and 3 exhibited antimicrobial activity against Staphylococcus aureus with IC50 1.5 and 3.5 μg/mL, respectively, and against Methicillin-resistant S. aureus with IC50 2.0 and 4.0 μg/mL, respectively.Keywords
This publication has 1 reference indexed in Scilit:
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