Structure and synthesis of pyrrolomycin A. a chlorinated nitro-pyrrole antibiotic.

Abstract
Pyrrolomycin A, a new antifungal antibiotic produced by an actinomycete, has a molecular formula C4H2N2O2Cl2. Its structure was determined to be 2,3-dichloro-4-nitropyrrole by spectroscopic analysis and synthetic studies. Structure-activity relationships among the analogs of pyrrolomycin A are discussed.

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