Cognitive Behavioral Analysis System of Psychotherapy and Brief Supportive Psychotherapy for Augmentation of Antidepressant Nonresponse in Chronic DepressionThe REVAMP TrialAugmentation With CBASP and BSP for Depression
Open Access
- 1 November 2009
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 66 (11) , 1178-1188
- https://doi.org/10.1001/archgenpsychiatry.2009.144
Abstract
The past decade has witnessed significant advances in the treatment of chronic depression. Several antidepressant medications1 and forms of psychotherapy2,3 have shown efficacy. Still, approximately 50% of chronically depressed patients in intent-to-treat analyses fail to respond to an adequate trial of antidepressant medication or psychotherapy, and an additional 20% do not obtain complete remission.1,4-6 This is important because residual symptoms are associated with significant functional impairment7 and increased risks of relapse and recurrence.8-10Keywords
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