Human Leukocyte-derived Alpha-Interferons: Purification and Amino-terminal–Amino-Acid Sequence of Two Components

Abstract
Multiple species of human alpha interferon derived from human leukocytes isolated from the buffy coat fraction of whole blood and induced with Sendai virus have been identified. Two species differing in molecular weight have been purified to homogeneity and the first 24 amino terminal amino acid residues have been shown to be identical in the two components.