Adsorption of Mycobacteriophage on Cell-wall Components

Abstract
Heat-killed whole cells, purified cell walls, and the three main polymers isolated from cell walls of Mycobacterium sp. atcc 607, M. smegmatis atcc 14468 and M. phlei atcc 11758, were examined to find the receptor sites for phage GS-7. Among heat-killed whole cells of insusceptible species, M. smegmatis adsorbed the phage at a higher rate than the susceptible Mycobacterium sp. atcc 607, whereas M. phlei did not adsorb the phage at all, suggesting a distinction between phage-resistance (absence of receptor) and phage-immunity (presence of both receptor and repressor).

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