Glutamic-Oxaloacetic Transaminases in Reticulocytes and Erythrocytes

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Abstract
In rabbits, mature erythrocytes contain only the anionic isozyme of glutamic-oxaloacetic transaminase. Reticulocytosis induced by massive bleeding or by treatment with acetylphenylhydrazine is characterized by a five- to sixfold increase in red-cell transaminase and the appearance of a cationic transaminase isozyme that apparently resides in the mitochondrial fraction of reticulocytes.