The sexual glands and metabolism

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Abstract
For the preparation of lipoid extracts, bulls'' testes and prostates were used; 102 rats (of which 92 were castrated and 10 normal) and 11 rabbits (6 normal, 2 castrated and 3 thyroidectomized) were used. The author describes a method for the isolation of lipoid fractions of the prostate and testis which were effective in raising the N metabolism. While these fractions were little if at all active when injected separately, when injected simultaneously they increased the N metabolism of rabbits sometimes as much as 20 %. This increase was obtained in only half the experi-ments. Changes of urinary flow were considerable but inconsistent. None of the fractions isolated from the prostate or testes injected singly or mixed in the doses given prevent the atrophy of the penis, seminal vesicles and prostate of castrated rats or produce hypertrophy of the genital organs of normal rats.

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