Isolation and structural determination of mutagenic substances in coal tar.

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Abstract
Eleven compounds that were mutagenic to Salmonella typhimurium TA98 were isolated from a basic fraction of coal tar. These were six aminopolycyclic aromatic hydrocarbons, 1-aminofluoranthene, 1- and 3-aminophenanthrene, 1- and 2-aminopyrene and 5-aminobenz [a] anthracene, and five aza-polycyclic aromatic hydrocarbons, phenaleno [1, 9-gh] quinoline, pyrido [3, 2-c] carbazole, quino [3, 2-c] carbazole, benzo [h] naphtho [2, 1, 8-def] quinoline and benzo [de] naphtho [1, 8-gh] quinoline.

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