Synthesis and biological activity of L-5-deazafolic acid and L-deazaaminopterin: synthetic strategies to 5-deazapteridines
- 1 December 1983
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 48 (25) , 4852-4860
- https://doi.org/10.1021/jo00173a014
Abstract
No abstract availableThis publication has 9 references indexed in Scilit:
- Pyrido[2,3-d]pyrimidines. The synthesis of the 5-deaza analogs of aminopterin, methotrexate, folic acid, and N10-methylfolic acidThe Journal of Organic Chemistry, 1982
- BIOCHEMICAL AND PHARMACOLOGIC PROPERTIES OF A NEW FOLATE ANALOG, 10-DEAZA-AMINOPTERIN, IN MICE1982
- A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in micePublished by Elsevier ,1981
- Folic acid analogs. III. N‐(2‐[2‐(2,4‐diarnino‐6‐quinazolinyl)ethyl]benzoyl)‐l‐glutamic acidJournal of Heterocyclic Chemistry, 1979
- Synthesis of quinazoline analogs of folic acid modified at position 10Journal of Medicinal Chemistry, 1977
- A new synthetic route to quinazoline analogs of folic acidJournal of Heterocyclic Chemistry, 1975
- The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agentsBiochemical Pharmacology, 1967
- Properties of Reduced Derivatives of AminopterinJournal of Biological Chemistry, 1964
- ASSOCIATION OF INCREASED DIHYDROFOLATE REDUCTASE WITH AMETHOPTERIN RESISTANCE IN MOUSE LEUKEMIA1962