Drugs for the treatment of hypercalcaemia

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Abstract
Summary: Hypercalcaemia is ordinarily treated by treatment of the underlying disorder. In some cases, as in malignant disease, in vitamin D poisoning and after a failed parathyroidectomy, the hypercalcaemia itself needs to be treated. A large number of methods have been advocated for this, but phosphate is the drug of choice in most patients. This paper outlines its use, mode of action and side effects and reviews the other methods proposed for the management of hypercalcaemia.