Treponemal Antigens in Congenital and Acquired Syphilitic Nephritis
- 1 September 1976
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 85 (3) , 325-327
- https://doi.org/10.7326/0003-4819-85-3-325
Abstract
Two patients, a 4 mo. old infant girl with congenital syphilis and a 45 yr old man with secondary syphilis, had the nephrotic syndrome with glomerulonephritis. Immunoglobulins and treponemal antigenic material were seen in the glomeruli of both patients by immunofluorescence microscopic studies of renal tissue. Electron micrographs showed subepithelial electron dense deposits along the glomerular basement membrane. The renal is apparently of an immune-complex type.Keywords
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