Silyl Ketene Acetal Chemistry: Steric Limitations in Lewis Acid-Promoted Addition of Ketones
- 1 April 1983
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 13 (6) , 449-458
- https://doi.org/10.1080/00397918308081822
Abstract
Lewis acid-promoted additions of ketones to silyl ketene acetals is limited sterically with α-branched alkyl groups in the ketone. Cyclic ketones give high yields. Titanium, ferric and aluminum chlorides are effective catalysts.Keywords
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