STREPTOMYCIN IN TREATMENT OF CLINICAL TUBERCULOSIS

Publisher Website
Google Scholar
Abstract
This is the 4th article by this group of authors dealing with the subject, and details various features experienced in the treatment of 75 cases, rather than being an over-all evaluation of the drug. Particularly good results have been observed in the handling of tuberculosis of the larynx by direct application, and in the cases of draining tuberculous sinuses. In 24 cases of pulmonary tuberculosis, although healing of the process was not obtained, it was believed that the streptomycin was effective in halting an unfavorable trend in the disease. The authors believe that streptomycin exerts a definite suppressive effect on tuberculosis in man, and show that the possibilities of acquired drug-fastness and other factors serve to limit the intensity and duration of its antibacterial properties. While suggesting that the drug is the first clinically feasible antibiotic remedy for tuberculosis, it is emphasized that accepted therapeutic practice, of proved value, cannot be relaxed.