Intratumor distribution of blood flow and of vascular volume in a transplantable rat sarcoma
- 1 December 1980
- journal article
- research article
- Published by Springer Nature in Zeitschrift für Krebsforschung und Klinische Onkologie
- Vol. 98 (3) , 213-219
- https://doi.org/10.1007/bf00410785
Abstract
The intratumor distribution of plasma volume and of blood flow was studied simultaneously by radioisotope techniques in a transplantable, slightly differentiated 20-methylcholanthrene-induced rat sarcoma. A significant change toward lower tumor blood flow was found in the sarcoma with increasing tumor growth, accompanied by a reduced plasma volume. The distributions of plasma volume and blood flow were similar in peripheral and central parts of tumors. However, no significant correlation between plasma volume and blood flow was found in separate tumor specimens.Keywords
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