Addition of Caspofungin to Fluconazole Does Not Improve Outcome in Murine Candidiasis
Open Access
- 1 July 2003
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 47 (7) , 2373-2375
- https://doi.org/10.1128/aac.47.7.2373-2375.2003
Abstract
Caspofungin is a potent antifungal inhibiting glucan synthesis in Candida species. However, caspofungin is not 100% curative in candidiasis. Therefore, we evaluated combinations of fluconazole with caspofungin for murine candidemia. We could not show any benefit of combined therapy over individual antifungal drugs.Keywords
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