Studies on the active conformation of the NK1 antagonist CGP 49823. Part 21. Fluoro-olefin analogs of tertiary amide rotamers.
- 4 February 1997
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 7 (3) , 351-354
- https://doi.org/10.1016/s0960-894x(96)00624-5
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- SAR of 2-benzyl-4-aminopiperidines: CGP 49823, an orally and centrally active non-peptide NK1 antagonistBioorganic & Medicinal Chemistry Letters, 1996
- Synthesis of phenyl substituted fluoro-olefinsTetrahedron Letters, 1996
- Fluoroolefin containing dipeptide isosteres as inhibitors of dipeptidyl peptidase IV(CD26)Tetrahedron, 1996
- Synthetic studies towards proline amide isosteres, potentially useful molecules for biological investigationsTetrahedron, 1996
- Fluoroalkenes as Peptide Isosteres: Ground State Analog Inhibitors of ThermolysinThe Journal of Organic Chemistry, 1995
- Fluoroolefin peptide isosteres - tools for controlling peptide conformationsTetrahedron Letters, 1994
- Fluoroolefin dipeptide isosteres -II. : Enantioselectlve synthesis of both antipodes of the phe-gly dlpeptide mimicTetrahedron Letters, 1990
- Fluoroolefin dipeptide isosteres — I.Tetrahedron Letters, 1990
- Synthesis of α- and γ-fluoroalkylphosphonatesJournal of the Chemical Society, Perkin Transactions 1, 1986
- Synthetic studies towards complex diterpenoids—VITetrahedron, 1972