Effects of nitrous oxide on the functional characteristics of cells in the extrastriate cortex of the cat

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Abstract
Summary The directional preferences, receptive field areas, peristimulus-time (PST) histograms and spontaneous activities of 112 feline visual cortical (area 18) cells were studied before, during, and after the administration of nitrous oxide. These cellular characteristics were altered by nitrous oxide inhalation; some quite substantially. The data indicate that the functional characteristics of cortical visual cells, such as the receptive field and the directional preference, are variable; and, among other factors, depend also on the anaesthetic administered to the animal.