Osteoporosis and African American Women
- 1 June 1999
- journal article
- review article
- Published by Mary Ann Liebert Inc in Journal of Women's Health & Gender-Based Medicine
- Vol. 8 (5) , 609-615
- https://doi.org/10.1089/jwh.1.1999.8.609
Abstract
The incidence of osteoporosis and related fractures in African American women is half that of Caucasian women. African American women who sustain osteoporosis-related fractures have increased disability and decreased survival. Given the exponential increase in hip fracture rate among African American women over the age of 70 years, the risk of osteoporosis among this population may be underestimated. This review focuses on racial differences in women's bone mineral density (BMD) and bone metabolism and on various explanations for these observed differences. Environmental risk factors for osteoporosis and related fractures among African American women and modalities for prevention and treatment of osteoporosis are discussed. African American women begin menopause with higher BMD and have lower rates of women's bone loss after menopause, which account for their decreased incidence of osteoporosis and related fractures. The risk factors for osteoporosis among African American women are similar to those found in Caucasian women. Lifestyle interventions, such as calcium and vitamin D supplementation, smoking cessation, and increased physical activity, should be encouraged to enhance peak bone mass and to decrease bone loss. These interventions and other treatment modalities, such as hormone replacement therapy, bisphosphonates, and selective estrogen receptor modulators, should be studied further in African American women.Keywords
This publication has 66 references indexed in Scilit:
- Effects of Raloxifene on Bone Mineral Density, Serum Cholesterol Concentrations, and Uterine Endometrium in Postmenopausal WomenNew England Journal of Medicine, 1997
- Vitamin D Receptor Gene Polymorphisms, Bone Turnover, and Rates of Bone Loss in Older African‐American WomenJournal of Bone and Mineral Research, 1997
- Medical Expenditures for the Treatment of Osteoporotic Fractures in the United States in 1995: Report from the National Osteoporosis FoundationJournal of Bone and Mineral Research, 1997
- Drug-related falls in the older adultTopics in Geriatric Rehabilitation, 1996
- Exercise effects on bone mass in postmenopausal women are site-specific and load-dependentJournal of Bone and Mineral Research, 1996
- Estrogen replacement therapy and coronary heart disease: A quantitative assessment of the epidemiologic evidencePreventive Medicine, 1991
- Effect of Fluoride Treatment on the Fracture Rate in Postmenopausal Women with OsteoporosisNew England Journal of Medicine, 1990
- Diminished Rates of Bone Formation in Normal Black AdultsNew England Journal of Medicine, 1988
- Differences in outcome between black and white elderly hip fracture patientsJournal of Chronic Diseases, 1987
- Decreased Risk of Fractures of the Hip and Lower Forearm with Postmenopausal Use of EstrogenNew England Journal of Medicine, 1980