Correlation of findings on transvaginal sonography with serum CA 125 levels.

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Abstract
This study was performed to correlate findings on transvaginal sonography with differential levels of serum CA 125.The study population included 144 patients who underwent transvaginal sonography for suspected pelvic mass and in whom a serum CA 125 level was established as part of the diagnostic workup. Levels of less than 36 U/ml were considered nonelevated; levels equal to or greater than 36 U/ml but less than 50 U/ml were considered mildly elevated; levels of 50-100 U/ml, moderately elevated: and levels greater than 100 U/ml, markedly elevated. Seventy-eight patients had pathologically proven gynecologic disease. Sixty-six patients were followed up with serial sonograms; benign gynecologic disease was diagnosed in 39 of these patients. In the 5-year period included in the study, the patients followed up with serial sonograms were imaged an average of 2.6 times during 2.1 years.Transvaginal sonography had a sensitivity of 97%, a specificity of 97%, and an overall accuracy of 94% for correctly revealing ...

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