Bone disorders following total gastrectomy

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Abstract
Bone disorders following gastrectomy were studied by measuring absolute and relative bone mineral density of the Wards triangle, serum 1,25-(OH)2-D, alkaline phosphatase, and total serum calcium. The subjects were 20 males who had undergone total gastrectomy not more than three months previously (group A1). Seventeen of these patients were reviewed three years later (group A2). Absolute and relative bone density were significantly lower in group A2 than in A1 (0.52 ± 0.011 g/cm2 versus 0.6 ± 0.014 g/cm2,PP2-D was significantly lower in group A2 than in group A1 (14.3 ± 0.97 pg/ml versus 20.6 ± 1.02 pg/ml,Pr=−0.74,P2-D and absolute or relative bone density (r=0.67,r=0.62 andP2-D deficiency. As no differences in serum alkaline phosphatase and serum calcium concentration were found, these factors are of little value for the early detection of postgastrectomy bone disorders, whereas weight loss is a valuable screening parameter.