CORNEAL TRANSPLANTATION REACTION IN AVASCULAR KERATOCONUS PATIENTS DUE TO HLA-ASSOCIATED IMMUNE ABERRATION AGAINST INFECTION - HYPOTHESIS

  • 1 January 1977
    • journal article
    • research article
    • Vol. 16  (7) , 644-646
Abstract
HL-A-B12 and HL-A-B27 appeared to be characteristic of avascular keratoconus patients at risk of developing a corneal allograft reaction, which was mainly of the late type and triggered by a nasopharyngeal infection. Equally incompatible grafts to patients with HL-A-B5 had an uneventful course. This may be an inference to the role of HL-A-associated immune resistance factors, which necessitate the search for histocompatible corneal grafts and for avascular recipients bearing such indicators of risk.

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