Properties of cytochrome P450 isoenzymes and their substrates part 2: properties of cytochrome P450 substrates

This publication has 15 references indexed in Scilit:

• Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: rationalization of CYP1A substrate specificity in terms of active site amino acid residues
  Xenobiotica, 1996
• Intermolecular interactions of antimicrobial fluoroquinolones with purified rat liver CYP1A2 studied by proton nuclear magnetic resonance spectroscopy
  Xenobiotica, 1996
• Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site
  Biochemistry, 1994
• Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily
  Biochemical Pharmacology, 1994
• The role of S‐mephenytoin 4'‐hydroxylase in imipramine metabolism by human liver microsomes: a two‐enzyme kinetic analysis of N‐ demethylation and 2‐hydroxylation.
  British Journal of Clinical Pharmacology, 1994
• Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies
  Journal of Medicinal Chemistry, 1993
• Speculations on the Substrate Structure-Activity Relationship (SSAR) of cytochrome P450 enzymes
  Biochemical Pharmacology, 1992
• The role of lipophilicity in the inhibition of polymorphic cytochrome P450IID6 oxidation by beta-blocking agents in vitro
  Life Sciences, 1991
• Physical Methods in the Study of the Active Site Geometry of Cytochromes P-450
  Drug Metabolism Reviews, 1986
• The hydrophobic interaction is long range, decaying exponentially with distance
  Nature, 1982