Inactivation of Transmissible Spongiform Encephalopathy (Prion) Agents by Environ LpH
Open Access
- 15 February 2004
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 78 (4) , 2164-2165
- https://doi.org/10.1128/jvi.78.4.2164-2165.2004
Abstract
Agents causing transmissible spongiform encephalopathy (TSE) diseases are resistant to inactivation by several conventional decontamination methods. Using an animal bioassay, we compared the TSE agent disinfectant efficacy of a commercially available product referred to alternatively as LpH-SE, LpH-AG, or LpH-st to that of a similarly named but differently formulated product, Environ LpH, which was found to be an effective TSE agent disinfectant in a previous study. Here, we found LpH-SE to be at least 104-fold to 105-fold less effective than Environ LpH.Keywords
This publication has 3 references indexed in Scilit:
- New studies on the heat resistance of hamster-adapted scrapie agent: Threshold survival after ashing at 600{degrees}C suggests an inorganic template of replicationProceedings of the National Academy of Sciences, 2000
- Inactivation of Transmissible Degenerative Encephalopathy Agents: A ReviewThe Veterinary Journal, 2000
- Comparative analysis of scrapie agent inactivation methodsJournal of Virological Methods, 1993