Depressed contractile function in reperfused canine myocardium: metabolism and response to pharmacological agents

Publisher Website
Google Scholar
Abstract
Regional myocardial function was measured with miniature ultrasonic crystals before, during, and after 10 min of coronary occlusion in anaesthetised open-chest dogs. In normal myocardium, intracoronary isoprenaline (0.1 μg·min−1) increased contraction velocity during the first third of systole (early systolic velocity) from 13.8±2.5 to 19.4±3.9 mm·s−1·cm−1, (P3·min−1·g−1 (P3·min1·g−1, (P−1·cm−1 (P −1·cm−1 (P 3·min1-·g−1 (P3·min−1·g−1(P per se, but is consistent with calcium overload during the period of reperfusion.

This publication has 5 references indexed in Scilit: