A Novel Route to Preussomerins via 2-Arylacetal Anions
- 2 May 2000
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 2 (11) , 1613-1616
- https://doi.org/10.1021/ol005881t
Abstract
Dimerization of salicylaldehydes provided 6H,12H-6,12-epoxydibenzo[b,f][1,5]dioxocins in multigram quantities. Deprotonation−allylation of the benzylic acetals followed by further functionalization of the diallyl derivative and double Friedel−Crafts cyclization gave a novel preussomerin analogue which possessed the full carbon skeleton of the natural products.Keywords
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