Gene Dosage and Linezolid Resistance in Enterococcus faecium and Enterococcus faecalis
Open Access
- 1 October 2002
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 46 (10) , 3334-3336
- https://doi.org/10.1128/aac.46.10.3334-3336.2002
Abstract
Resistance to linezolid has been associated with a G2576U mutation in domain V of the 23S rRNA. We analyzed nine clinical isolates of linezolid-resistant enterococci and showed a clear association between the number of 23S rRNA genes containing this mutation and the level of linezolid resistance expressed.Keywords
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