Effect of Thyrotropic Hormone on the Iodination of Thyroglobulin in Pig Thyroid Slices
- 1 August 1961
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 50 (2) , 145-150
- https://doi.org/10.1093/oxfordjournals.jbchem.a127422
Abstract
The iodination-accelerating effect of thyroid-stimulating hormone (TSH) is approximately proportional to the logarithmic concentration of TSH, though the dose-response ratio varies considerably from one thyroid gland to another. The TSH effect is counteracted by 0.003 M KCN, 10-4 M 2,4-dinitrophenol, 0.01 M ethylenediaminetetraacetate, 10-3 M KSCN, ascorbic acid, methylmercaptoimidazole, and dithiodiethyl-carbamate.Keywords
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