Application of a Ring Closing Metathesis Based Linker to the Solid Phase Synthesis of Oligosaccharides

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Abstract
A linker allowing a ring closing metathesis mediated cleavage of resin bound oligosaccharides in the form of their 1-O-allyl derivatives was designed. This new linker system for the solid phase synthesis of oligosaccharides via the trichloroacetimidate approach demonstrated highly promising results.

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