The detection by cellular electrophoresis of surface antibodies on human lymphocytes.

  • 1 December 1969
    • journal article
    • Vol. 5  (6) , 669-72
Abstract
The electrophoretic mobility of peripheral blood lymphocytes from human subjects with positive Mantoux tests was measured before and after treatment with purified protein derivative. Lymphocytes from subjects with negative Mantoux reactions were used as controls. A large number of the first group lymphocytes showed a reduction of electrophoretic mobility and hence of the surface electrical charge. The mobility of the control cells submitted to the same treatment was unchanged. The possible presence of cytophilic antibodies or of cellular specific receptors on the lymphocyte surface is discussed.