Salivary Secretion in Evolutive and Quiescent Duodenal Ulcer

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Abstract
The outputs of some salivary components were compared in 9 healthy subjects and in 9 patients suffering from a duodenal ulcer. In both groups the study was performed twice. Patients with a duodenal ulcer were studied for the first time when the ulcer was evolutive and for the second time when it was healed. In comparison with controls, the salivary outputs of fucose, hexosamines and sulfate were lower in patients with an evolutive duodenal ulcer; a larger part of calcium was then found in the bound form. In contrast to this, all salivary outputs were greater in patients with healed duodenal ulcer than in controls; after recovery, the distribution pattern of calcium was the same as that observed in healthy subjects. It is assumed that the diminished salivary secretion, observed in patients with an evolutive duodenal ulcer, is a transient abnormality whereas the increased secretion measured in patients with healed ulcer could be related to the enlargement of their salivary glands.

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