RADIATION-DOSE CALCULATIONS IN PERSONS RECEIVING INJECTION OF SM-153 EDTMP

  • 1 April 1987
    • journal article
    • research article
    • Vol. 28  (4) , 505-509
Abstract
Samarium-153 EDTMP has been proposed as a radionuclide therapeutic agent to treat malignant bone tissue disorders. Data obtained from laboratory rats has been used to calculate the radiation dose for humans following the administration of [153Sm]EDTMP. The data reveals that the highest doses are present in the skeleton and the urinary bladder wall (bladder doses varies with frequency of voiding). Skeletal activity was used to estimate the bone marrow dose from the [153Sm]EDTMP beta radiation. Although this estimate idicates high marrow irradiation it is only an approximation since the beta radiation from inhomogeneously deposited bone activity surrounding the marrow produces variable radiation dose distributions.

This publication has 1 reference indexed in Scilit: