Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases
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Open Access
- 31 December 2004
- journal article
- research article
- Published by Elsevier
- Vol. 12 (12) , 2233-2247
- https://doi.org/10.1016/j.str.2004.10.004
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Crystal Structure of Human Phosphodiesterase 3B: Atomic Basis for Substrate and Inhibitor SpecificityBiochemistry, 2004
- Crystal Structures of the Catalytic Domain of Phosphodiesterase 4B Complexed with AMP, 8-Br-AMP, and RolipramJournal of Molecular Biology, 2004
- Crystal Structures of Phosphodiesterases 4 and 5 in Complex with Inhibitor 3-Isobutyl-1-methylxanthine Suggest a Conformation Determinant of Inhibitor SelectivityJournal of Biological Chemistry, 2004
- Cyclic nucleotide research — still expanding after half a centuryNature Reviews Molecular Cell Biology, 2002
- Imidazo[5,1- f ] [1,2,4] triazin-4(3 H )-ones, a new class of potent PDE 5 inhibitorsBioorganic & Medicinal Chemistry Letters, 2002
- IC351 (tadalafil, Cialis): update on clinical experienceInternational Journal Of Impotence Research, 2002
- Efficient anisotropic refinement of macromolecular structures using FFTActa Crystallographica Section D-Biological Crystallography, 1999
- Adaptation in cyclic AMP signalling processes: A central role for cyclic AMP phosphodiesterasesSeminars in Cell & Developmental Biology, 1998
- Improved methods for building protein models in electron density maps and the location of errors in these modelsActa Crystallographica Section A Foundations of Crystallography, 1991
- Aromatic-Aromatic Interaction: A Mechanism of Protein Structure StabilizationScience, 1985