Methotrexate for corticosteroid-resistant polymyalgia rheumatica and giant cell arteritis
- 1 May 1989
- journal article
- research article
- Published by Cleveland Clinic Journal of Medicine in Cleveland Clinic Journal of Medicine
- Vol. 56 (3) , 253-257
- https://doi.org/10.3949/ccjm.56.3.253
Abstract
Three patients (one with polymyalgia rheumatica with jaw claudication and two with biopsy-proven giant cell arteritis) were initially treated using prednisone (40-60 mg daily). The response was good in all three, but each experienced exacerbation of symptoms and elevation of Westergren sedimentation rates (WSR) with dose reduction. The addition of methotrexate (7.5-12.5 mg/wk) resulted in diminished symptoms and lower WSR and proved to be steroid-sparing.This publication has 0 references indexed in Scilit: