Temporal Bone Findings in Cryptococcal Meningitis

Abstract
• A 19-year-old woman with cryptococcal meningitis died as a result of her disease, in spite of both intravenous and intraventricular administration of amphotericin B. Gross and microscopic examinations revealed multiple cysts containingCryptococcus neoformanswithin the central nervous system. Studies of the temporal bones revealed both neural and end organ destruction with the presence ofCryptococcuswhen stained by Gomori methenamine silver nitrate method. We present the results of audiometric and vestibular examinations. The case history depicts a progressive neurological involvement byCryptococcus. (Arch Otolaryngol101:577-583, 1975)

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