The Preparation and Antifungal Activity of Some Salicylic Acid Derivatives
- 1 September 1957
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 9 (1) , 855-863
- https://doi.org/10.1111/j.2042-7158.1957.tb12347.x
Abstract
A series of 2-alkoxy derivatives of benzamide, halogenated benzamides, 3-naphthamide, and N-substituted benzamides has been prepared and tested in vitro as potential antifungal agents. 2-n-Amyloxybenzamide, the most active of the derivatives studied, is a slow-acting fungicide of greater fungistatic potency than undecylenic acid, N-n-butyl-3-phenyl-salicylamide, salicylanilide, Nystatin, phenylmercuric acetate, sodium ethylmercurithiosalicylate and 8-hydroxyquinoline.Keywords
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