Statistical Characteristics and Normal Values of Four Serum Enzymes, Glutamic Oxalacetic Transaminase, Glutamic Pyruvic Transaminase, Aldolase, and Creatine Phosphokinase

Abstract
Levels of glutamic oxalacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), aldolase (ALD), and creatine phosphokinase (CPK) have been measured in healthy subjects. No effect of age has been found, but there is a sex difference. Males have higher levels than females. Except for GOT and GPT none of the enzymes show correlated levels. The logarithm of enzyme level is found to be better than the original value for statistical purposes. Confidence intervals for normal values are given for each enzyme. A method of evaluating the joint significance of the results of one, two, three, or four enzymes is given. The values are combined into a single index, high levels of which indicate hyperenzymemia. A simple procedure for the statistical assessment of a given result is provided in table VII and figure 4.