Genomic Map of Clostridium perfringens Strain 13
- 1 February 2001
- journal article
- Published by Wiley in Microbiology and Immunology
- Vol. 45 (2) , 179-189
- https://doi.org/10.1111/j.1348-0421.2001.tb01278.x
Abstract
A physical and genetic map of Clostridium perfringens strain 13 was constructed. C. perfringens strain 13 was found to have a 3.1-Mb chromosome and a large 50-kb plasmid, indicating that strain 13 has a relatively small genome among C. perfringens strains. A total of 313 genetic markers were mapped on the chromosome of strain 13. Compared with the physical and genetic map of C. perfringens CPN50, strain 13 had a quite similar genome organization, but with a large deletion (approximately 400 kb) in a particular segment of the chromosome. Among several toxin genes, a beta2 toxin gene that is a novel virulence gene in C. perfringens was found to be located on the 50-kb plasmid.Keywords
This publication has 18 references indexed in Scilit:
- Identification of novel VirR/VirS‐regulated genes in Clostridium perfringensMolecular Microbiology, 2000
- Beta2 toxin, a novel toxin produced by Clostridium perfringensGene, 1997
- The virR/virS locus regulates the transcription of genes encoding extracellular toxin production in Clostridium perfringensJournal of Bacteriology, 1996
- Rapid expansion of the physical and genetic map of the chromosome of Clostridium perfringens CPN50Journal of Bacteriology, 1995
- Identification and molecular analysis of a locus that regulates extracellular toxin production in Clostridium perfringensMolecular Microbiology, 1994
- Genomic diversity and organization of virulence genes in the pathogenic anaerobe Clostridium perfringensMolecular Microbiology, 1992
- Basic local alignment search toolJournal of Molecular Biology, 1990
- Toxigenic clostridiaClinical Microbiology Reviews, 1990
- Genome organization of the anaerobic pathogen Clostridium perfringens.Proceedings of the National Academy of Sciences, 1989
- Stable L-forms of Clostridium perfringens and their growth on glass surfacesCanadian Journal of Microbiology, 1976