THE INHIBITION BY MORPHINE OF THE ACTION OF SMOOTH MUSCLE STIMULANTS ON THE GUINEA‐PIG INTESTINE
Open Access
- 1 September 1960
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology and Chemotherapy
- Vol. 15 (3) , 425-431
- https://doi.org/10.1111/j.1476-5381.1960.tb01267.x
Abstract
Morphine and related analgesics depress the responses of the isolated guinea-pig ileum to nervous stimulation and to drugs which act by stimulating the nervous structures of the intestinal wall. The present experiments show that these analgesics also depress the responses to smooth muscle stimulants which act directly on the smooth muscle fibres.Keywords
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