Synthesis and X-ray crystal structure of a new ‘cholaphane’ with externally directed functionality
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 9,p. 612-614
- https://doi.org/10.1039/c39910000612
Abstract
The ‘cholaphane’1 was synthesized in 26% overall yield from cholic acid and its structure determined by X-ray crystallography; the molecule adopts an open conformation and is able to surround two molecules of tetrahydrofuran.Keywords
This publication has 7 references indexed in Scilit:
- Artificial Receptors for Carbohydrate DerivativesAngewandte Chemie International Edition in English, 1990
- Synthesis of steroidal cyclodimers from cholic acid; a molecular framework with potential for recognition and catalysisJournal of the Chemical Society, Chemical Communications, 1989
- Asymmetric induction in carbonyl analogs: comments on modelsThe Journal of Organic Chemistry, 1984
- The chemistry of higher order organocupratesTetrahedron, 1984
- Syntheses with Unsaturated Nitriles; I. Selective Hydrolysis of 1-Amino-2,6,6-tricyano-1,3-cyclohexadienes to 2,6,6-Tricyano-2-cyclohexenonesSynthesis, 1980
- 2-tert-BUTYL-1,3-DIAMINOPROPANEOrganic Syntheses, 1973
- The Chemistry of Carbanions. XII. The Role of Copper in the Conjugate Addition of Organometallic Reagents1The Journal of Organic Chemistry, 1966