Resolution of Chronic Hepatitis B after Ritonavir Treatment in an HIV-Infected Patient

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Abstract
Spontaneous clearance of hepatitis B surface antigen (HBsAg) has been reported in about 5 percent of immunocompetent patients with chronic hepatitis B, but not in patients infected with human immunodeficiency virus (HIV).1 We describe an HIV-infected patient in whom treatment with the HIV-protease inhibitor ritonavir was associated with a flare of his chronic hepatitis B, followed by clearance of the virus and normalization of liver-enzyme levels.