Recognition-Directed Orthogonal Self-Assembly of Polymers and Nanoparticles on Patterned Surfaces

Abstract
We demonstrate the patterning of silica substrates with thymine (Thy-PS) and positively charged N-methylpyridinium (PVMP) polymers using photolithography and the subsequent orthogonal modification of these surfaces using diaminopyridine-functionalized polystyrene (DAP-PS) and carboxylate-derivatized CdSe/ZnS core−shell nanoparticles (COO-NP) through diamidopyridine−thymine three-point hydrogen bonding and pyridinium−carboxylate electrostatic interactions, respectively. This two-component orthogonal surface modification was accomplished in a self-sorting, single-step fashion, providing a versatile tool for the rapid and efficient creation of complex materials.